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Cholestasis is characterized by the accumulation of bile acids (BAs) in the liver and is often associated with severe itching (cholestatic pruritus (CP)). Activation of the GPCR hX4 in dorsal root ...

The World Health Organization ranks the severity of patients’ PAH according to functional classes I through IV, with I being the mildest and IV the most severe form of the disease. Winrevair’s ...

T.D.T., a 21-year-old man from Yen Bai, sought medical attention at the National Hospital for Tropical Diseases in Hanoi after experiencing fever, dizziness, nausea, severe itching, numbness, and ...

Eczema is a common group of skin conditions that result in inflamed, itchy patches on the skin. In severe cases, these patches may cause constant discomfort and open weeping sores. The most common ...

A severe thunderstorm warning was issued by the National Weather Service on Wednesday.The warning has now expired. More: See the current weather alerts for your countyInteractive radar ...

Many risk factors can lead to a stroke, but the magnitude of risk from some of these conditions or behaviors may have a stronger association with severe stroke compared with mild stroke ...

More Seattle homes were without power during the peak of the windstorm Tuesday than at any time in nearly 20 years, a city spokesperson said. At the peak Tuesday night, 114,000 Seattle City Light ...

as demonstrated by a statistically significant reduction from baseline in monthly itch score over 24 weeks versus placebo. The trial recruited PBC patients with moderate to severe itch, who were ...

The phase III linerixibat trial was made up of patients experiencing moderate to severe itch who were either receiving stable doses of guideline-suggested therapies for cholestatic pruritus ...

The trial met its primary endpoint, showing a statistically significant improvement in itch over 24 weeks compared to placebo. The GLISTEN trial recruited PBC patients experiencing moderate to severe ...