it’s possible that itching isn’t related to your liver disease. A severe case of dry skin (xerosis cutis) can certainly lead to troublesome itching. Itching without rash can also be a side ...

GSK has reported promising results with a drug to treat the severe itching that plagues patients with rare cholestatic liver disease primary biliary cholangitis (PBC). Interim results from the ...

Cholestasis is characterized by the accumulation of bile acids (BAs) in the liver and is often associated with severe itching (cholestatic pruritus (CP)). Activation of the GPCR hX4 in dorsal root ...

Clobetasol, triamcinolone, and fluocinonide are medications that may reduce severe inflammation and itching from poison ivy. When poison ivy causes severe reactions, over-the-counter (OTC ...

T.D.T., a 21-year-old man from Yen Bai, sought medical attention at the National Hospital for Tropical Diseases in Hanoi after experiencing fever, dizziness, nausea, severe itching, numbness, and ...

A 33-year-old Caucasian pregnant woman (26 weeks’ gestation) presented to the emergency department. She had a 2-day history of severe itching of the scalp and steadily worsening swelling of the face ...

The phase III linerixibat trial was made up of patients experiencing moderate to severe itch who were either receiving stable doses of guideline-suggested therapies for cholestatic pruritus ...

The drugmaker put the idea to the test in a phase 3 trial that randomized PBC patients with moderate to severe itch to receive linerixibat or placebo. GSK included people on stable doses of anti-i ...

Not all trials found a benefit, but the largest trial found that intrathecal injections led to excellent or good pain relief ...