Purpose: The effects of extreme temperatures on drug delivery of two albuterol sulfate hydrofluoroalkane, metered-dose inhalers (MDIs) were evaluated.Methods. Three Proventil HFA and three ...

The leak rates for the Proventil HFA test and control MDIs were similar ... dose per actuation for both MDIs is 108 µg of albuterol sulfate, which corresponds to 90 µg of albuterol base.

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