Similarities to the post-translational modification phosphorylation suggest that AMPylation may be an important regulatory mechanism. Post-translational modifications are key steps in the ...

Post-translational modifications are modifications that occur on a protein, catalysed by enzymes, after its translation by ribosomes is complete. Post-translational modification generally refers ...

The funding will be used to accelerate the development of the company’s technology that analyzes proteins and their post-translational modifications to predict the treatment responses of patients with ...

A major, but not exclusive focus of our lab is the analysis of histones, their variants, post-translational modifications and proteoforms. Histones are essential regulators of the human genome and ...

In a study published in Nature Methods, a research group developed a highly sensitive proteomics method called ...

These studies revealed structural determinants for recognition of consensus SUMO modification sequences found within SUMO conjugated proteins. Reconstituting SUMO conjugation in vitro revealed ...

Despite their therapeutic significance, the mechanism underlying the post-translational modification of a particularly robust class of these peptides remains largely unexplored. Using a ...

Biochemists at the National University of Singapore (NUS) have identified a new subclass of trifunctional enzymes in ...

This guide highlights how advanced analytical tools can uncover post-translational modifications, identify proteoform origins ...

The ICR's proteomics facility is among the most sophisticated in the UK, providing a highly-skilled specialist service using advanced mass spectrometry techniques ...