News Medical7 小时
Comparing Vericheck ddPCR and AUC for precise AAV therapeutic genome analysis
A commercial vendor received two AAV samples, one serotype 5 (AAV5) and one serotype 9 (AAV9). The two samples were generated ...
Texas Medical Center assessing different sites for BioPort manufacturing campus
Some cell manufacturing sites models do work closer to the Medical Center. Leger highlighted CTMC, a joint venture partially ...
The EMBO Journal1 小时
A split intein and split luciferase-coupled system for detecting protein-protein interactions
The split intein-mediated protein ligation (SIMPL) system for detecting protein-protein interactions has been enhanced by ...
The EMBO Journal4 小时
Cholesterol restriction primes antiviral innate immunity via SREBP1-driven noncanonical ...
Cholesterol restriction-mediated SREBP1 activation induces noncanonical type I IFNs, including IFN-ω and minor IFN-α subsets, ...
eLife23 小时
Rab10 inactivation promotes AMPAR insertion and spine enlargement during long-term potentiation
Among these sensors, we further focused on the spatiotemporal dynamics of Rab10 and Rab4 activity during sLTP. We found that postsynaptic stimulation leads to the persistent inactivation of Rab10 and ...