This work will be of high interest to a broad swathe of scientists studying native macromolecules present at low concentrations in cells. Cryo-EM single-particle analyses typically require target ...

The process is followed by computationally guided mutagenesis or evolution of the antibody sequence (hit to lead, or H2L, optimisation) to improve the binding and other properties. Although the ...

This study presents important findings on the role of CXXC-finger protein 1 in regulatory T cell gene regulation and function. The evidence supporting the authors' claims is solid, with mostly ...

Black Friday week is finally here and that means the gaming keyboard and gaming mouse deals are flowing in. After all, November now just seems to be a permanent sales month for all tech retailers ...

Yes, it's cheaper than the DeathAdder V3 Pro, but it still costs a pretty penny. If you're watching your pennies, the best budget wireless gaming mouse is Logitech's G305 Lightspeed.It doesn't ...

According to Alnylam’s Tim Mooney, mivelsiran’s endurance is due to stabilizing tweaks the scientists made to the siRNA ...

Nov. 22, 2024 — Geneticists have developed a gene drive-based solution to the widespread problem of insecticide resistance. In an effort to protect valuable crops, the researchers created an 'e ...

Boosting Brain Protein Levels May Slow Decline from Alzheimer's Sep. 11, 2024 — A study found that new monoclonal antibody drugs for Alzheimer's may slow cognitive impairment through boosting ...

Here, the authors applied single-cell RNA sequencing to characterize live neurons isolated from prion-infected mice and identified genes that may influence vulnerability.

MiXCR is an ultimate software platform for analysis of Next-Generation Sequencing (NGS) data for immune profiling.