Mitochondrial diseases, often stemming from complex genetic factors, impact the mitochondria's energy production. Japanese ...

Mitochondrial disease can be inherited through mutations in DNA that specifically affect mitochondrial function. About 50 Australian children are born every year with mitochondrial disease.

"We discovered that DNMT3A and TET2 mutations prevent their ability to bind and activate the TFAM gene, Missing or reducing this binding activity leads to mitochondrial DNA release and overactive ...

Mitochondrial DNA depletion syndrome (MTDPS) is a rare genetic disorder characterized by a marked decrease in mitochondrial DNA (mtDNA). This ...