MG132 offset the effect of empagliflozin on NLRP3 degradation; coimmunoprecipitation assay confirmed that empagliflozin promotes the degradation of NLRP3 through the ubiquitin-proteasome system (all ...

School of Life Sciences and Medicine, Shandong University of Technology, Zibo 255000, China ...

Ubiquitination, an essential post-translational modification, controls various cellular functions by attaching ubiquitin to proteins, dictating their fate from degradation to functional reorganization ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The functions of integrins are tightly ...

This valuable study focuses on gene regulatory mechanisms essential for hindbrain development. Through molecular genetics and biochemistry, the authors propose a new mechanism for the control of Hox ...

Mechanism studies revealed that syndecan‐4 induces PASMC proliferation by interacting and regulating protein kinase C α ubiquitination. In addition, syndecan‐4 was enriched in exosomes secreted from ...

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