HIV can destroy entire "families" of CD4 cells, and then the germs these cells fight have easy access to your body. The resulting illnesses are called opportunistic infections (OIs) because they ...

The test measures the level of CD4 helper T-cells in the blood—cells that are not only vital to immune function but are the primary target of HIV infection. As HIV gradually depletes these cells, the ...

When the CD4 count is below 100 or 50, a person may never reach normal levels even with treatment. To this end, it is important to get tested if you have risk factors for HIV whether you have symptoms ...

As the science stands, the vast majority of the roughly eight million people in South Africa living with HIV will have to get ...

The combination therapy of bictegravir/emtricitabine/tenofovir (BIC/FTC/TAF) was both tolerable and produced virologic ...

An immune response that likely evolved to help fight infections appears to be the mechanism that drives human ...

The decrease in CD4 cells during HIV infection seems to be driven by immune activation, which does not always correlate with viral load. Experienced clinicians are all too familiar with the ...

Your CD4 cell count drops, your HIV viral load rises again, and you become very infectious.‌ If you have AIDS, you will get other infections that become serious because your immune system is ...

an HIV glycoprotein complex consisting of glycoproteins gp41 and gp120 must bind with the CD4 receptor on the membrane of the host cell. This binding causes conformational changes in gp120 that ...

Women living with HIV can reduce their risk of cervical cancer using a human papillomavirus (HPV) vaccine that is both ...

The CCR5Δ32 variant reduces the expression of CCR5 receptors on CD4 + T cells, which HIV commonly uses to enter cells. Individuals carrying this variant exhibited lower CCR5 expression and lower rates ...