Summary: Astrocytes, critical brain cells, are often lost in neurodegenerative diseases, but recent research highlights the promise of astrocyte transplantation to restore brain function. These ...

In this work, the authors propose that astrocytic aquaporin 4 (AQP4) is the main pathway for tonic water efflux, without which astrocytes undergo cell swelling. These findings are important, because ...

But it turned out this wasn’t the whole picture. Williamson’s research investigated the role astrocytes, non-neuron brain cells, play in the read-and-write operations that go on in our heads.

The authors first show in acute brain slices, and in vivo with fiber photometry, SRB loaded astrocytes swell after inhibition of AQP4 with TGN-020, indicative of tonic water efflux from astrocytes in ...

Summary: Astrocytes, non-neuronal brain cells, have been shown to work alongside neurons to store and recall memories, reshaping our understanding of memory mechanisms. Researchers found that specific ...

Manipulating astrocytes’ acidity in mice influences memory retention, with acidification impairing and alkalinization preserving long-term memories, offering insights into memory treatment approaches.

This astrocyte-neuron communication flows both ways; astrocytes and neurons depend on each other." When mice were in a situation not associated with fear, they did not freeze.

Department of Environmental Medicine, University of Rochester Medical Center, 575 Elmwood Avenue, Rochester, New York 14620, United States ...