Role of the RAAS in the Pathophysiology of Heart Failure ACE inhibitors have no effect on angiotensin II formed by alternate pathways. In contrast, ARBs would be expected to inhibit the biologic ...

Angiotensin II (AT-II)-Receptor Antagonists are Reviewed. Research focused on blocking the renin- angiotensin system (RAS) led to the discovery of angiotensin-converting-enzyme (ACE) inhibitors ...

Conclusion: Partial or complete loss of Sca-1 worsens aortic remodeling in Ang-II HTN by increasing progenitor expansion and pro-fibrotic contributions. These data highlight a critical role for ...

From the development of new materials that make airplanes lighter to the exploration of alternative fuels, the aviation industry is making strides toward reducing its carbon footprint. One aspect ...

At AHA 2024, the safety of GLP-1R agonists in heart failure and chronic kidney disease (CKD) patients was discussed.

During the 1990s, medicinal chemist Anders Hallberg was working in his lab at the Department of Medicinal Chemistry. He was exploring a hormonal system in the body that regulates blood pressure, among ...

There is no shortage of ASX healthcare companies with upcoming catalysts – a focal point for investors. ... Read More The ...

They defined some physiological features of what they called the ascending reticular activating system, setting the scene for the discovery of the multifaceted roles of the reticular formation. In ...

Any guidance is based on very limited observational evidence and cut-offs are necessarily arbitrary. Angiotensin II causes a preferential increase in efferent arteriolar tone, helping to maintain GFR ...