A groundbreaking study has used patient-derived stem cells to recreate a rare genetic form of autism in the lab.

Chofflet et al. investigate the immunoglobulin superfamily member 21 (IgSF21)–neurexin2α (Nrxn2α) complex, a critical organizer of inhibitory synapses in the brain, and provided insights into the ...

Morris, like thousands of other customers, was snared in the collapse of a behind-the-scenes fintech firm called Synapse and has been locked out of her account for six months as of November.

Without effective inhibitory signaling ... a protein essential for presynaptic structure in excitatory, glutamatergic synapses. Lastly, researchers noted a decrease in the amplitude of miniature ...

“Sheila noticed that when applied onto NMDA receptors that were chronically active, ketamine had a stronger inhibitory effect than expected based on the ... “Moreover, the increase in excitation ...

This valuable study reports the existence of specific spike-timing dependent synaptic plasticity processes at two excitatory synapses of the dentate gyrus granule cells. These synapses link the ...

investigated the mechanisms of synaptic plasticity of two important hippocampal synapses, the excitatory afferents from lateral and medial perforant pathways ... (1) It should be clarified whether ...