This important study introduces rationally designed, genetically encoded tools for the selective and reversible ablation of excitatory and inhibitory synapses. The evidence is convincing, supported by ...

This work is a continuation of a previous paper from the Arnold group, where they engineered GFE3, which allows to specifically ablate inhibitory synapses. Here, the authors generate 3 different ...

Chofflet et al. investigate the immunoglobulin superfamily member 21 (IgSF21)–neurexin2α (Nrxn2α) complex, a critical organizer of inhibitory synapses in the brain, and provided insights into the ...

A groundbreaking study has used patient-derived stem cells to recreate a rare genetic form of autism in the lab.

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A new study reveals how NREM sleep enhances cognitive performance by synchronizing neural activity and improving information ...