In chronologically aged skin, the epidermis is atrophic, with flattening of the dermal-epidermal junction and loss of rete pegs (Kurban & Bhawan, 1990). The dermis also becomes thinner ...
A 42-year-old Black woman with no significant past medical history presents with blue-gray macules on her neck and upper chest that gradually developed over the past year.
Biopsy of a lesion reveals a band-like inflammatory lymphocytic infiltrate at the dermal-epidermal junction, basal keratinocyte vacuolar changes, and pigment incontinence and melanophages in the ...
A team has observed it for the first time in the form of condensates in keratinocytes, the cells of the epidermis. The presence of IL-38 in these aggregates is enhanced close to the skin's surface ...
As mentioned previously, epidermal and dermal melasma respond very differently to treatment. Coverup with opaque cosmetics remains essentially the only option for dermal melasma. An exception to ...
It takes a multifaceted approach to protect the dermal-epidermal junction. Active ingredients including dipalmitoyl hydroxyproline and antioxidants improve elasticity, reduce the appearance of ...