suggesting splenic B cells were modulating adverse cardiac remodeling via major histocompatibility complex class II (MHC II)-mediated antigen presentation (Figure 2). Therefore, we developed ...

Cancer Res (2024) 84 (22_Supplement): B023.

As noted above, stellate cell activation is the central event ... in matrix protease activity play an important role in ECM remodeling accompanying fibrosing liver injury (see section on ...

CAFs rely on protease- and force-mediated ECM remodeling to facilitate tumor cell invasion and metastasis. Moreover, the hypoxic TME regulates ECM remodeling by CAFs, with HIF-1α-expressing CAFs ...

Nov. 21, 2024 — Researchers have analyzed the entire mouse intestine, mapping gene expression and cell states and location in the healthy gut and in response to perturbations such as inflammation.

Background: Vascular remodeling to match arterial diameter to tissue metabolic requirements commonly fails in ischemic disease. Endothelial cell (EC) sensing of elevated fluid shear stress ... Results ...

Pathogens cause severe diseases that lead to human death and health complications. In the pathogenesis of infectious diseases, cell migration and tissue remodeling play crucial roles, influencing the ...

When complex multicellular organisms grow and develop, their tissues must undergo remodeling ... with isolated single-cell apoptosis transitioning to more clustered apoptosis.

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Nov. 18, 2024 — An international team of researchers has achieved an unprecedented milestone: the creation of mouse stem cells capable of generating a fully developed mouse using genetic tools ...