They identify three distinct signalling pathways responsible for this effect, involving direct action on smooth muscle cells, as well as indirect modulation via interneurons or astrocytes. This work ...

Researchers from the University of Illinois have discovered a key factor responsible for facilitating signal transduction in Cys-loop receptors, providing insight into a longstanding question in the ...

The lab of Hassane Mchaourab, director of the Center for Applied Artificial Intelligence in Protein Dynamics and professor of ...

The funding, provided through the Allen Distinguished Investigators, a program of The Paul G. Allen Frontiers Group at the Allen Institute, will fuel innovative research in Organelle Communication and ...

This study provides valuable insights into the differential impact of intrinsic and synaptic conductances on circuit robustness, emphasizing intrinsic plasticity as a crucial but often overlooked ...

The B-cell lymphoma 2 (Bcl-2) family of proteins finely regulates mitochondrial integrity, affecting outer membrane permeability and the apoptosis process (Czabotar and Garcia-Saez, 2023). This family ...

This image provided by Ana-Maria Cujba shows blood vessels in a portion of the human small intestine, March 21, 2024. (Ana-Maria Cujba/Wellcome Sanger Institute via AP) This image provided by Nathan ...

Established in 2016, the Human Cell Atlas (HCA) consortium set out to create a comprehensive biological map of cells within the human body. Now progressing into a data integration phase ...

Scientists published more than three dozen papers as part of the Human Cell Atlas, an effort to map the human body cell by cell. The human body contains around 36 trillion to 37 trillion cells ...

An ambitious plan to map all 37 trillion cells in the human body is transforming understanding of how our bodies work, scientists report. The received wisdom said we were built from around 200 ...

The T-vant adjuvant is derived from bacterial outer membrane vesicles ... spurring the activation of immune cells in the respiratory tract critical for halting the bacteria’s ability to colonize.