Methods Quantitative PCR, western blotting, immunohistochemistry and immunofluorescence were used to study the expression pattern of Wnt2 and its effect on the Wnt/β-catenin pathway. A Wnt2-secreting ...

LMU researchers have discovered how the interplay between a key protein and an endolysosomal ion channel promotes tumor ...

Faith and righteousness through Jesus Christ defined; freedom from sin's power; conflict between our fleshly and spiritual natures. Likewise reckon ye also yourselves to be dead indeed unto sin . . . ...

The dual signaling pathways of NRF2 and FXR cooperatively regulate bile acid metabolic homeostasis through the interaction mechanism with β-catenin/P300.

LMU researchers have discovered how the interplay between a key protein and an endolysosomal ion channel promotes tumor development in skin cancer.

We discovered that TGR5-dependent bile acid signalling unexpectedly strengthens biliary epithelial barrier function, both in vitro and in vivo. We identified a yet unreported pathway in which BAs ...