These CENP-A proteins ensure that divided genetic information is kept intact during mitosis.

Chemotherapy targets cancer cells by disrupting DNA replication and mitotic processes, despite side effects on healthy cells.

Research shows mitochondria form distinct subpopulations under nutrient stress, revealing survival mechanisms in cancer cells ...

Enzyme: This game-changing protein might be the key to understanding how our cells divide and why cancer happens. Here's what ...

Asymmetric cell division can be divided into four main steps ... worms are relevant for understanding self-renewing normal and cancer stem cells. The review also includes a brief discussion ...

DNA catapults into spotlight. A trio of research papers from Stanford Medicine researchers and their international collaborators transforms scientists’ understanding of how small DNA circles — until ...

Cancer works by leveraging the body’s existing ... and is involved in mitosis (the division of cells for replication) under even extreme body conditions like neoplastic (tumor) growth.

As the hunt for effective cancer therapies intensifies, some scientists are turning back to look at old drugs in a new light.

Researchers at the Centre (CRG) reveal that metabolic enzymes known for their roles in energy production and nucleotide synthesis are taking on unexpected "second jobs" within the nucleus, ...

Plants, fungi and bacteria produce a variety of bioactives that alter cell metabolism, sometimes to the point of cell death.

Metabolic enzymes, typically associated with energy production, are now discovered to also play essential roles in the nucleus, such as orchestrating cell division and DNA repair. This breakthrough, ...

Optune Lua creates tumor-treating fields to disrupt cancer cell division, and it is used in conjunction with PD-1/PD-L1 inhibitors or docetaxel to treat metastatic non–small cell lung cancer ...