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COPD is a syndrome akin to asthma but with important differences, including tobacco smoke-induced pathobiology and pulmonary emphysema. An exploration of how best to define ACOS is beyond the ...

Objective: To investigate the efficacy and tolerability of high-dose N-acetylcysteine (NAC) in the treatment of patients with exacerbations of chronic obstructive pulmonary disease (COPD).