On page 1086, Kuroiwa et al. describe a chromosome-cloning system that can handle large segments of genomic DNA. They cloned large fragments of human chromosomes into a mitotically stable human ...

To tackle the conundrum, Yingjin Yuan, a professor of biochemical engineering at Tianjin University, turned to deoxyribonucleic acid (DNA) and has designed yeast artificial chromosomes as a ...

Moreover, artificial chromosomes, unlike relatively cramped viral vectors, would permit the expression of large, cooperative ...

And now they’ve hit a major milestone by managing to combine artificial versions of some of the 16 chromosomes in a single yeast cell successfully. This feat is especially exciting because it ...