Figure 1: AFM techniques to characterize and manipulate biological systems on the nanometre scale. Molecular interactions make up the basic language of all biological processes. They determine how ...

Real-time HS-AFM observation of Aβ fibril growth and the 4396C antibody binding at the fibril end Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to ...

They’ve begun safety studies of a monoclonal antibody that would, ideally, stop D68 in its tracks. “In mouse studies, it ...

The process of alternating elongation and pausing of amyloid β (Aβ) fibrils was captured by combining high-speed atomic force microscopy (HS-AFM) and Monte Carlo simulations. The study revealed ...

Once the antibody binds, the fibril is locked in this ... The detailed high-resolution observations made with HS-AFM allowed the research team to uncover this alternating growth and pause ...