In the early phase of Alzheimer’s disease, astrocytes are the primary source of APOE in the brain. This study examined the effects of astrocyte-derived human APOE isoforms in APOE-deficient mouse ...

Summary: Astrocytes, critical brain cells, are often lost in neurodegenerative diseases, but recent research highlights the promise of astrocyte transplantation to restore brain function. These ...

This important study demonstrated that ablation of astrocytes in the lumbar spinal cord not only reduced neuropathic pain but also caused microglia activation. The findings presented add considerable ...

Summary: Astrocytes, non-neuronal brain cells, have been shown to work alongside neurons to store and recall memories, reshaping our understanding of memory mechanisms. Researchers found that specific ...

Manipulating astrocytes’ acidity in mice influences memory retention, with acidification impairing and alkalinization preserving long-term memories, offering insights into memory treatment approaches.

Baylor College of Medicine scientists discovered that astrocytes contribute to memory, challenging the neuron-focused model. Astrocytes, when activated, can stimulate memory recall in specific ...

The Baylor team expanded this theory by showing that non-neuronal cell types in the brain called astrocytes – star-shaped cells – also store memories and work in concert with groups of neurons called ...

The Baylor team expanded this theory by showing that non-neuronal cell types in the brain called astrocytes—star-shaped cells—also store memories and work in concert with groups of neurons ...

This work is important because it highlights the potential importance of circadian rhythms in astrocytes, even though making a direct comparison between these rhythms in vitro and in vivo remains ...