Background In the CLARITY AD study, lecanemab was shown to reduce markers of amyloid and slow cognitive decline at 18 months in early Alzheimer’s disease (AD). Here, we report the initial findings ...

1 Department of Neurology, University of Iowa, Iowa City, Iowa, USA 2 Department of Neurology, University of Minnesota, Minneapolis, Minnesota, USA Correspondence to: Dr Praful Kelkar, Department of ...

Background Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL) is a hereditary cause of cerebral small-vessel disease associated with one of many ...

Correspondence to Dr Michael Benatar, Department of Neurology, University of Miami Miller School of Medicine, Miami, Florida, USA; MBenatar{at}med.miami.edu Notwithstanding the challenges, it is ...

Department of Medicine, University Hospital, Nottingham, UK. Data from 357 conscious stroke patients taking part in an acute intervention trial and assessed within 48 hours of the onset of symptoms, ...

Objective There is still an urgent need for supportive minimally invasive and cost-effective biomarkers for early diagnosis of Alzheimer’s disease (AD). Previous work in our lab has identified ...

Background The aim of this study was to determine treatment response and whether it is associated with antibody titre change in patients with autoimmune nodopathy (AN) previously diagnosed as chronic ...

Objective: Parkinson’s disease (PD) is a progressive neurological disorder characterised by a large number of motor and non-motor features that can impact on function to a variable degree. This review ...

Correspondence to Dr Ya Miao, Department of Geriatrics, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China; nning-my{at}163.com; Prof Qihao Guo, Department of Geriatrics ...

Background For more than 15 years, deep brain stimulation (DBS) has served as a last-resort treatment for severe treatment-resistant obsessive-compulsive disorder (OCD). Methods From 2010 to 2016, 20 ...

Department of Neurosurgery, University of Mississippi Medical Center, Jackson, Mississippi, USA Dr J Zhang, Department of Neurosurgery, University of Mississippi Medical Center, 2500 N State Street, ...

Advanced neuroimaging has increased understanding of the pathogenesis and spread of disease, and offered new therapeutic targets. MRI and positron emission tomography have shown that neurodegenerative ...