Bigner, MD, PhD Faillot and coworkers [21] also performed a phase I study to evaluate whether a single IV injection could deliver an adequate amount of anti-EGFR monoclonal antibody (MAb 425 ...

Explore the challenges and advancements in anti-EGFR antibody treatment for metastatic colorectal cancer. Discover how ...

“Portrazza (Necitumumab), an IgG1 Monoclonal Antibody, FDA Approved for Advanced Squamous Non–Small-Cell Lung Cancer.” Translational Lung Cancer Research: “Treatment of uncommon EGFR ...

monoclonal antibodies, such as cetuximab and panitumumab, directed against the extracellular domain of EGFR, and tyrosine kinase inhibitors, like gefitinib and erlotinib, which block the kinase ...

Clazakizumab, a monoclonal antibody that targets the inflammatory ... endpoint (1-year estimated glomerular filtration rate [eGFR] slope-;a measure of changes in kidney function) accepted by ...