Type 2 diabetes (T2D) and obesity (OB) are associated with chronic low-grade inflammation and increased fracture risk. In vitro studies showed that inflammation induces bone erosion and inhibits bone ...

These signalling systems operate beyond cell and tissue boundaries, but function as morphogens that are secreted from one cell or tissue type to activate surface receptors, signal transduction ...

When he added the Wnt-coated beads to dishes in which embryonic stem cells were growing, the scientists could then watch individual cells that were close enough to a bead to receive a Wnt3a signal, ...

Surrozen, Inc. (“Surrozen” or the “Company”) (Nasdaq: SRZN), a company pioneering targeted therapeutics that selectively activate the Wnt pathway for tissue repair and regeneration, today announced a ...

To understand why, the researchers looked at blood vessels from the brains of infected mice to see which genes were most altered. They found a significant decrease in a signaling pathway called ...