The efficacy of trastuzumab deruxtecan after endocrine-based therapy in patients with metastatic breast cancer with low expression of human epidermal growth factor receptor 2 is unknown.
Aditya Bardia, MD, MPH, FASCO, discusses how fam-trastuzumab deruxtecan-nxki compares with physician’s choice of chemotherapy in estrogen receptor-positive/HER2-low breast cancer.