Transforming growth factor-beta (TGF-β), a well-known morphogen ... "Given the high conservation of TGF-β signaling, manipulating TGF-β pathways to coordinate mitochondrial stress responses ...
The transforming growth factor beta (TGF-beta) pathway regulates vascular remodeling and mutations in its receptor genes, TGFBR1 and TGFBR2, cause syndromes with thoracic aortic aneurysm (TAA).
Dysfunctional TGF-Beta is a major contributor to lung diseases ... in 2016 to develop therapeutics for targets in the Wnt pathway, a key signaling pathway that is involved in embryo development ...
Currently, we are working with Orange Grove Bio and Station 41 to continue this drug development pathway. One of our therapeutic targets is renal fibrosis. To this end, Orange Grove Bio has ...
Surrozen, Inc. (“Surrozen” or the “Company”) (Nasdaq: SRZN), a company pioneering targeted therapeutics that selectively activate the Wnt pathway for tissue repair and regeneration, today announced a ...
Jefferies initiated coverage of Keros Therapeutics (KROS) with a Buy rating and $107 price target The firm says Keros has expertise in the TGF-beta pathway, which plays roles in blood, lung and ...