TGF-β signaling pathway mediates neuronal-intestinal mitochondrial stress response and lipid metabolism, finds study
Transforming growth factor-beta (TGF-β), a well-known morphogen, is recognized for its role in regulating growth and ...
Nature5y
TGF-β insensitivity promotes proliferation and invasion in esophageal adenocarcinoma
while remaining responsive to TGF-β-mediated activation of kinase signaling pathways. TGF-β could, therefore, be independently involved in both the initiation and progression of esophageal ...
Business Insider20d
Surrozen and TCGFB, Inc. Announce Strategic Research Collaboration to Develop TGF-β Antibodies for Idiopathic Pulmonary Fibrosis
TCGFB will own all TGF-β product related intellectual ... to overcome the limitations in pursuing the Wnt pathway as a therapeutic strategy, and the potential for the modulation of the Wnt signaling ...
FierceBiotech19d
The Column Group's biotech taps Surrozen for lung disease research pact
TCGFB is paying Surrozen up to $6 million, plus any third-party costs, for antibodies that target transforming growth factor beta ... targets in the Wnt pathway, a key signaling pathway that ...
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Loeys-Dietz Syndrome & PIP Eligibility
Understanding LDS is crucial for early diagnosis and management, which can significantly improve the quality of life for ...
Joplin Globe2d
Spine BioPharma, Inc. to Present at the Piper Sandler 36th Annual Healthcare Conference
Spine BioPharma, Inc., a development stage company committed to non-opiate, non-surgical therapies for Degenerative Disc Disease (DDD), today announced that Chief Executive Officer Marc Viscogliosi ...
Medical Xpress1mon
TGF-β signaling pathway mediates neuronal-intestinal mitochondrial stress response and lipid metabolism, finds study
Additionally, all components of the TGF-β Dauer signaling pathway are required for the activation of systemic UPR mt. Further investigations revealed that inhibiting daf-7 function in just a pair ...