Our prototype synthetic peptide, CTTHWGFTLC, inhibits the migration of human endothelial cells ... tumors. Finally, we show that CTTHWGFTLC–displaying phage specifically target angiogenic blood ...
T cells are white blood cells that are important for adaptive ... T cells to sense and respond to diverse types of infection. Tumor-infiltrating T cells are known to encounter chronic antigens ...
T argeting and customizing blood vessels in tumors to increase T cell infiltration and maintain their function may represent the next breakthrough in cancer therapy. The European Research Council ...
Aside from providing oxygen and nutrients to the tumor, blood vessels also secrete angiocrine factors. This study revealed that the factor Sfrp1, produced by vascular endothelial cells ...
First, defects in EC cell cycle control may impact normal migration against the blood flow. Alternatively, EC cell cycle defects may impact arteriovenous specification. In addition, the ...