Here the authors characterise bone marrow cells from PRCA patients by single cell sequencing showing hyperactive CD8 + T cells ... the difference between CD4 + T cell responses to self and ...

Whereas spleen cells from the remaining ... dependent on post-transplant administration of CD8+ T cells. Survival of mice treated, with either CD4- or CD8-depleted DLI, as indicated.

CD4-cell counts and T-cell activation levels were determined ... and higher LPS levels were associated with greater activation of CD8 + lymphocytes. CD8 + activation also was found to be higher ...