The disease gets its name because when you have SCD, your red blood cells look like a sickle, which is a C-shaped farm tool. Normal red blood cells are round and pliable. With sickle cell ...

The majority of SCD patients given Lyfgenia in clinical trials remained free of vaso-occlusive events (VOEs) following ...

Cyclosporin H Improves the Transduction of CD34+ Cells with an Anti-Sickling Globin Vector, a Possible Therapeutic Approach for Sickle Cell Disease. Credit: Mary Ann Liebert, Inc.

As he got older, he learned he had sickle cell disease: His red blood cells were forming sickle shapes and getting stuck in his blood stream, preventing oxygen from reaching his tissues.

The most-read gene therapy articles included topics on FDA approvals, chimeric antigen receptor T-cell therapies, the ...

Sickle cell disease (SCD) is a pressing global health issue, with rising cases and mortality, especially in low- and middle-income countries (LMICs). Hydroxyurea, a cost-effective treatment for ...

Nigerian woman opens up about the struggles of living with sickle cell disease, sharing her story to raise genotype ...

A breakthrough at the Lagos University Teaching Hospital, Idi-Araba, has brought cheery news to people with sickle cell disease. LUTH doctors working with an NGO, Sickle Cell Foundation of Nigeria ...

Called Casgevy, the gene-editing treatment is for people with sickle cell disease and a related blood disorder called beta thalassemia. UK regulators approved the treatment in November 2023 ...

SAN DIEGO — The approval one year ago of two genetic medicines for sickle cell disease, including the first therapy powered by CRISPR gene editing, was a milestone for people living with a ...

MTL-HBG is an RNAa medicine designed to increase transcription of the gamma globin gene (HBG), enabling people with sickle cell disease to produce enhanced levels of fetal hemoglobin (HbF).