San Francisco 49ers tight end George Kittle told reporters he had "no idea" why he received just two targets during a 35-10 ...

The San Francisco 49ers may soon lose one of their best offensive players to the Minnesota Vikings in free agency.

The wife of San Francisco 49ers offensive tackle Trent Williams announced their son, Trenton O'Brien Williams Jr., was ...

As injuries once again define a 49ers NFC title defense, the team still has some silver linings in the form of defenders ...

As injuries once again define a 49ers NFC title defense, the team still has some silver linings in the form of defenders ...

NFL analyst reports that the 49ers and Raiders are the top suitors for free agent quarterback Daniel Jones following his ...

The offensive line of the San Francisco 49ers hasn't been too shabby this season. But that doesn't mean they can't use some ...

San Francisco 49ers head coach provides a minor update on Brock Purdy's injury following a brutal loss to the Green Bay ...

Josh Allen grabbed at his left hand and jumped in pain after he took on 49ers linebacker De'Vondre Campbell Sr.

Kyle Shanahan announced that the 49ers ruled out All-Pro defensive end Nick Bosa and starting quarterback Brock Purdy for ...

San Francisco 49ers general manager John Lynch appeared on Bay Area radio station KNBR on Friday morning to share the latest ...

The NFL weather report for Bills vs. 49ers predicting non-stop snow but the league has zero plans to postpone the game.