The management of rheumatoid arthritis (RA) with biological response ... and interleukin-1 (IL-1), play a critical role in the pathogenesis of this disorder. IL-1-receptor antagonist (IL-1Ra ...

RA-ILD significantly increases mortality, with a median survival of less than 3 years post-diagnosis. Key risk factors ...

While some studies suggest that Black Americans get rheumatoid arthritis (RA) at around the same rate as white people, some ...

The company has made significant progress in expanding its lead asset, IMVT-1402, into rheumatoid arthritis (RA) with plans for a ... supported by expert opinions on the disease’s pathogenesis and ...

There is a bidirectional association for rheumatoid arthritis (RA ... present the results for genetic predisposition, the shared pathogenesis between the two diseases indicates the importance ...

CP-690550 is a novel immunosuppressant and a small-molecule inhibitor of Janus kinase 3 (JAK3), a key enzyme in cytokine signal transduction implicated in rheumatoid arthritis pathogenesis.