The management of rheumatoid arthritis (RA) with biological response ... and interleukin-1 (IL-1), play a critical role in the pathogenesis of this disorder. IL-1-receptor antagonist (IL-1Ra ...

CP-690550 is a novel immunosuppressant and a small-molecule inhibitor of Janus kinase 3 (JAK3), a key enzyme in cytokine signal transduction implicated in rheumatoid arthritis pathogenesis.

While some studies suggest that Black Americans get rheumatoid arthritis (RA) at around the same rate as white people, some ...

There is a bidirectional association for rheumatoid arthritis (RA ... present the results for genetic predisposition, the shared pathogenesis between the two diseases indicates the importance ...

RA-ILD significantly increases mortality, with a median survival of less than 3 years post-diagnosis. Key risk factors ...

into rheumatoid arthritis (RA) with plans for a pivotal study, and the clearance of five investigational new drug applications (INDs). This expansion into RA indicates a substantial market opportunity ...