Baylor College of Medicine1y
Patient-Derived Xenograft Core
The primary focus Patient-Derived Xenograft (PDX) Core is to develop, and provide to the Baylor PDX community, computational and bioinformatics infrastructure to support large scale generation, ...
BioWorld2d
Researchers develop humanized xenograft glioblastoma model in mice
Researchers have described the development of a novel murine model of glioblastoma established with a patient-derived xenograft (PDX) in humanized mice that harbored an almost complete human immune ...
Ensem Therapeutics To Present Preclinical Data for Potential Best-in-Class Oral CDK2 Inhibitor at San Antonio Breast Cancer Symposium
Ensem Therapeutics, Inc. (ENSEM), a pioneering drug discovery and development company that leverages its unique Kinetic ...
FierceBiotech29d
23andMe shutters cancer drug research programs, lays off 40% of staff
while 23ME-01473 slowed the growth of non-small cell lung cancer in a patient-derived xenograft mouse model. 23andMe intertwines with Branson's Virgin Group to go public in $3.5B SPAC deal The ...
Baylor College of Medicine4y
Patient-Derived Xenograft Core Publications
Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidates for targeted treatment. Nat Commun. 2021 Aug 24;12(1):5086. Erratum in: Nat Commun. 2022 Jan 7;13(1):294.