Unfortunately, unlike animal studies, neuropathic pain mechanisms in humans remain largely unclear; current clinical and neurophysiological research has proposed various mechanisms for each type ...

People with depression may be more prone to experiencing period pain, potentially due to genetic factors in part, a new study ...

However, researchers have been unable to explain the specific mechanism behind this deficiency. In this paper, the researchers propose that psychopaths' inability to learn from painful outcomes could ...

When pain signals are passed along the nervous system, proteins called calcium channels play a key role. Researchers at ...

Pain signals travel through the nervous system with the help of proteins known as calcium channels, which play a crucial role ...

Injuries to the somatosensory system may give rise to neuropathic pain. Injuries can occur at any interval along the neuraxis, but the most common locations are the peripheral and dorsal root ...

6 Arthritis Research UK Primary Care Centre, Research Institute for Primary Care & Health Sciences and Keele Clinical Trials Unit, Keele University, Staffordshire, UK The need for pain to be avoided ...

greater benefits could be gained in the future by targeting newly discovered pain mechanisms. We used single-soma deep RNA sequencing to generate a high-resolution atlas of human somatosensory ...

The mechanism of action for the targeted prodrug ... which are present in much higher amounts at sites of pain than the rest of the body. This means that the prodrug, designed and made in ...