Adding to the ever-growing list of newly discovered bacterial immune systems, we have characterized the mechanisms of an ...

As Dbp5 shuttles, it could interact with Yra1 within the nucleus. The final steps in mRNA export consist of removing proteins from the mRNP and transferring the mRNA to the translation machinery.

Exporting the mRNA from inside the nucleus to the site of protein translation in the cytoplasm is a critical step for life for eukaryotes like us. Yi Ren's most recent paper, published in eLife ...

近年来，mRNA疗法展现出独特优势和巨大潜力，在肿瘤治疗新药开发与临床应用领域成为全世界的研究热点。2023年，诺贝尔生理学或医学奖授予mRNA技术的两位奠基人——卡塔琳·考里科和德鲁·韦斯曼。 “mRNA技术的可行性、快速响应能力与大规模生产能力已得到 ...

Messenger RNA carries genetic information from DNA in the highly protected nucleus out to the rest of the cell, where structures called ribosomes can build proteins according to the DNA blueprint.

Insights into protein synthesis processes in prokaryotes and eukaryotes are crucial for advancements in genetics, ...

The mRNA never goes into the nucleus of your cells where your DNA is stored. The newly made spike protein now sits on the surface of the muscle cells. Your immune system senses the spike protein ...

In more complex human cells, DNA resides in the walled-off nucleus, where RNAP serves as the "interpreter," breaking down ...

When a gene is to be expressed, the base sequence of DNA is copied or transcribed into mRNA (messenger RNA). This process takes place in the nucleus and occurs in a series of stages. The two ...

Use precise geolocation data and actively scan device characteristics for identification. This is done to store and access ...

Expert Rev Vaccines. 2012;11(1):55-67. A summary of the events taking place after intradermal injection of naked mRNA is given inFigure 1. Although formulation of mRNA vaccines and sophisticated ...