A cell signaling mechanism of fundamental importance to animal development is the Notch pathway (Figure 1). It may be safely said that Notch signaling is required, in some reasonably direct fashion, ...
The Notch signaling pathway is central to a wide array of developmental processes in a number of organ systems, including hematopoiesis, somitogenesis, vasculogenesis, and neurogenesis.
"The Notch signaling pathway, and the immune cells involved, is not only well-conserved across species, but also across ...
The interplay between hormone signaling and malignant transformation remains incompletely understood. This study identifies ...
Spinal development, however, is controlled by an oscillating process that is dependent on a group of genes in the Notch pathway, only some of which have homologues in the Drosophila segmentation ...
As a post-doctoral researcher at Yale University and at the Institute for Molecular Biology and Biotechnology on Crete, Greece, she studied functions of the Notch signaling pathway during nervous ...
His team has also learned how a set of signals called the Notch pathway prompt blood stem cells to multiply. A Fred Hutch spinoff, Nohla Therapeutics, is now building on this discovery to develop ...
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