The Notch signaling pathway is central to a wide array of developmental processes in a number of organ systems, including hematopoiesis, somitogenesis, vasculogenesis, and neurogenesis.

A cell signaling mechanism of fundamental importance to animal development is the Notch pathway (Figure 1). It may be safely said that Notch signaling is required, in some reasonably direct fashion, ...

The authors therefore proposed that targeting this vital step in Notch pathway signalling may represent a new therapeutic approach. First, using phage display technology, the authors generated ...

BACKPACKOriginal ArticleTitle:Dual-function natural products: Farnesoid X receptor agonist/inflammation inhibitor for ...

"The Notch signaling pathway, and the immune cells involved, is not only well-conserved across species, but also across ...

which differentiate into bile duct epithelial cells (called the Notch signaling pathway). However, the molecular mechanism by which bile duct epithelial cells differentiate only along the portal vein ...

As a post-doctoral researcher at Yale University and at the Institute for Molecular Biology and Biotechnology on Crete, Greece, she studied functions of the Notch signaling pathway during nervous ...