Assuming that mitochondria evolved from bacteria, they looked for two known bacterial PAMPs: DNA and formyl peptides. In one experiment, they measured the release of mitochondrial DNA into the ...

Mitochondrial DNA depletion syndrome (MTDPS) is a rare genetic disorder characterized by a marked decrease in mitochondrial ...

Mitochondrial diseases, often stemming from complex genetic factors, impact the mitochondria's energy production. Japanese ...

Researchers used mitochondrial gene editing to model genetic disorders in mice, revealing profound impacts on brain function, ...

Mitochondria possess their own DNA (mtDNA), which plays important roles in cellular respiration and energy consumption.

Mitochondrial DNA (mtDNA)-encoded RNA molecules undergo extensive processing to generate mature RNA, including removal of ...

Mitochondrial DNA depletion syndrome (MTDPS) is a rare genetic disorder characterized by a marked decrease in mitochondrial DNA (mtDNA). This ...

Mitochondrial disease can be inherited through mutations in DNA that specifically affect mitochondrial function. About 50 Australian children are born every year with mitochondrial disease.

"We discovered that DNMT3A and TET2 mutations prevent their ability to bind and activate the TFAM gene, Missing or reducing this binding activity leads to mitochondrial DNA release and overactive ...