The 3 most prevalent mutation detection methodologies are DNA sequencing, gene chip arrays, and the line probe assay. The gene chip and line probe assays are commonly grouped together as "probe ...

Molecular assays enable the rapid detection of mutations that confer resistance. Line-probe assays have been shown to exhibit a high accuracy for the detection of rifampicin resistance (and ...

Simultaneously, the accuracy of the diagnostic results of WGS will be validated vis a vis gold standard diagnostic testing method, namely Liquid culture Drug Susceptibility Testing (LCDST) and Line ...