Proventil HFA and Ventolin HFA MDIs both delivered a decreased amount of drug as the temperature increased ( 4). The amount of drug delivered from the Proventil HFA MDI at 60°C was 14.8% less ...

Purpose: The effects of extreme temperatures on drug delivery of two albuterol sulfate hydrofluoroalkane, metered-dose inhalers (MDIs) were evaluated.Methods. Three Proventil HFA and three ...