Sheep were used by the team as the physiology of their hearts is similar to human hearts. When the animals had heart failure – induced by pace makers – which was sufficiently advanced to need ...

Congestive heart failure is a disease state distinguished by the regular presence of both renal and hepatic abnormalities in drug handling. One such abnormality involves flaws in the process of ...

Using a gene-screening method they created, Stanford Medicine researchers may have discovered why an effective chemotherapy ...

A commonly prescribed medication for heart failure was linked to a lower risk of heart damage, or cardiotoxicity, among high-risk cancer patients undergoing chemotherapy treatment using anthracyclines ...

The combination of sacubitril and valsartan reduces the cardiotoxicity related to anthracycline chemotherapy drugs, according ...

Cardiac fibrosis is a frequent comorbidity in many diseases, such as ischemic heart failure or diabetes mellitus, contributing to increased mortality. No drugs are approved for cardiac fibrosis ...

A drug used to help patients lose weight and manage diabetes may also help those with heart failure, an international clinical trial shows. The test of tirzepatide, brand named Zepbound ...

The drug, from pharmaceutical company Eli Lilly and Co., was tested in the SUMMIT clinical trial at 146 sites in the United States and abroad. A total of 731 patients with diastolic heart failure ...

Drug discovery researchers have found that a natural fat molecule called 'lipoxin A4' (LXA4) could significantly reduce inflammation and improve function for diabetic hearts.

Weight-loss and diabetes drug tirzepatide can reduce the risk of death or worsening heart failure for patients with heart failure, preserved heart pump function and obesity, new research from UVA ...

Monash University drug discovery researchers have found that a natural fat molecule called "lipoxin A4" (LXA4) could ...