Regarding bone health, Advisory Committee of the FDA concluded that dapagliflozin has minimal ... filtered glucose is about 125 mg/min. Main action of SGLT2 inhibitors is the induction of ...

Combination regimens based on SGLT2 inhibitors and two drugs with different mechanisms of action have shown activity ... the combination of its SGLT2 drug dapagliflozin with zibotentan, an ...