The team have employed in silico methods to identify candidate inhibitors, structural and biochemical methods to evaluate inhibitor effectiveness in vitro and microbiological susceptibility assays to ...
A clear area (zone of inhibition) indicates that the bacteria have been killed by the solution or have not been able to reproduce. Soak small (5 mm) filter paper disks in a variety of solutions ...
Researchers from the University of Washington are developing new antibiotics targeting bacterial methionyl-tRNA synthetase (MetRS). This enzyme is responsible for charging tRNA(met) with methionine ...
A propylamine modification increases antibacterial activity of and target inhibition by McC. The YejABEF peptide transporter provides the only route of McC entry into enteric bacteria. McC is ...