Mutant BCL6 will abnormally situate near genes that trigger apoptosis ... This method aims to turn on a pathway that is normally off, instead of inhibiting something that promotes cancer. "Since ...
Scientists working in a lab. Image source: chokniti / Adobe One of the main proteins used in the new procedure is called BCL6, and when it mutates, it actually drives blood cancer. Medical ...
Image: the BCL6 BTB domain dimer (in grey/green) and compound hits in pink, superimposed on each other in the main compound binding site. Dr Rob van Montfort lab / ICR Scientists have revealed details ...