And now they’ve hit a major milestone by managing to combine artificial versions of some of the 16 chromosomes in a single yeast cell successfully. This feat is especially exciting because it ...
On page 1086, Kuroiwa et al. describe a chromosome-cloning system that can handle large segments of genomic DNA. They cloned large fragments of human chromosomes into a mitotically stable human ...
Human artificial chromosomes (HACs) capable of working within human cells could power advanced gene therapies, including ...
To tackle the conundrum, Yingjin Yuan, a professor of biochemical engineering at Tianjin University, turned to deoxyribonucleic acid (DNA) and has designed yeast artificial chromosomes as a ...
He is also credited with the construction of the world’s first yeast artificial chromosome. That feat helped scientists to map the location of genes in mammals and to develop techniques for ...
If large fragments of genomic DNA averaging 100-300 kb need to be microinjected, then Bacterial Artificial Chromosome (BAC) clones harboringlarge genomic DNA fragments (100-300 Kb) can allow faithful ...