Glioblastoma multiforme is an extreme example. Antiangiogenic therapy has been combined with radiotherapy with mixed results: additive or synergistic tumor growth delay, or reduced response.

However, lack of response to antiangiogenic drugs and adverse drug reactions leading to treatment suspension are critical clinical problems that need to be solved. Because antiangiogenic drugs act ...

Right now, the best way to do that is with anti-angiogenic therapy. This can slow or stop vision loss from abnormal blood vessel growth, even improving eyesight for some people. During treatment ...

Benefits of photodynamic therapy for wet AMD. This treatment is used less often now that the more effective and safer anti-angiogenic medications are available. But your doctor may recommend that ...

which indicate that the antiangiogenic effects of bevacizumab might persist despite the development of resistance to first-line chemotherapy. For decades, cancer therapy has been rooted in the ...

Treatment options for patients with glioblastoma multiforme (GBM), the most common form of malignant gliomas, now include anti-angiogenic therapy after failure of standard multi-modality treatments.

Angiopoietin-2 (ANGPT2) is a ligand of the receptor tyrosine kinase TIE2 (TEK). In conjunction with vascular endothelial growth factor (VEGF), ANGPT2-TIE2 signaling induces vascular sprouting.